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What happens when stereocilia are bent?

What happens when stereocilia are bent?

, bending of the stereocilia toward the kinocilium—depolarizes the hair cells and increases the rate of discharge. Deflection away from the utricle causes hyperpolarization and decreases the rate of discharge. In superior canals these effects are reversed.

When the stereocilia of a hair cell in the inner ear bends it causes?

Bending the cilia in one direction causes the cell membrane to depolarize, while hyperpolarization… The sensory cells are called hair cells because of the hairlike cilia—stiff nonmotile stereocilia and flexible motile kinocilia—that project from their apical ends.

How does the movement of stereocilia cause depolarization of the hair cell?

When tension increases, the flow of ions across the membrane into the hair cell rises as well. Such influx of ions causes a depolarization of the cell, resulting in an electrical potential that ultimately leads to a signal for the auditory nerve and the brain.

What bends the stereocilia?

Cochlear Excitation and Homeostasis. OHC stereocilia are bent by a shearing force that occurs when up-and-down movements of the basilar membrane cause it to slide relative to the tectorial membrane, a jelly-like sheet that covers the organ of Corti and in which many OHC stereocilia are embedded.

What is the difference between Kinocilium and Stereocilia?

The kinocilium is inserted eccentrically on top of the sense cell; the stereocilia are arranged in parallel rows. In about half of the hair cells of a neuromast, the kinocilium is found on one (and the same) side…

Do inner hair cells have stereocilia?

Inner hair cells transduce basilar membrane vibration into electrical activity. Basilar membrane vibration causes stereocilia on the surface of inner hair cells to bend (see Fig. 1.1, Chapter 1).

Do hair cells release neurotransmitter?

The neurotransmitter released by hair cells that stimulates the terminal neurites of peripheral axons of the afferent (towards the brain) neurons is thought to be glutamate. Efferent synapses occur on outer hair cells and on afferent axons under inner hair cells.

What happens when inner hair cells are damaged?

Sensory hair cells of the inner ear are exposed to continuous mechanical stress, causing damage over time. This damage can manifest in many forms, from dysfunction of the hair cell mechanotransduction complex to loss of specialized ribbon synapses, and may even result in hair cell death.

What do inner hair cells do?

Inner hair cells (IHCs), the sensory cells of the cochlea, are responsible for signal transduction. Lying in a single row along the internal side of the tunnel of Corti, they are connected to type I spiral ganglion neurons (of which the axons represent about 95% of auditory nerve fibres).

What is the difference between inner hair cells and outer hair cells?

The main difference between inner and outer hair cells is that the inner hair cells convert sound vibrations from the fluid in the cochlea into electrical signals that are then transmitted via the auditory nerve to the brain whereas the outer hair cells amplify low-level sounds that enter into the fluids of the cochlea …

What is the function of inner and outer hair cells?

structure and function The inner hair cells are sensory, and the nerves extending from them send acoustic information to the brain. In contrast, the outer hair cells are motile and have a role in amplifying and modifying the movement of the basilar membrane.