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What happens if amino acid sequence is changed?

A missense mutation is a mistake in the DNA which results in the wrong amino acid being incorporated into a protein because of change, that single DNA sequence change, results in a different amino acid codon which the ribosome recognizes. Changes in amino acid can be very important in the function of a protein.

Why is the sequence of amino acids important to protein function?

The linear sequence of amino acids within a protein is considered the primary structure of the protein. The chemistry of amino acid side chains is critical to protein structure because these side chains can bond with one another to hold a length of protein in a certain shape or conformation.

What might happen if a protein has a change in one amino acid quizlet?

What might happen if a protein has a change in one amino acid? The protein has a new shape.

What would happen if one amino acid is substituted for another one in a polypeptide give a specific example?

Explain what happens if even one amino acid is substituted for another in a polypeptide chain. A change in gene sequence can lead to a different amino acid being added to a polypeptide chain instead of the normal one. This causes a change in protein structure and function.

What would be an expected consequence of changing one amino acid in a protein consisting of 325 amino acids *?

What would be an unexpected consequence of changing one amino acid in a protein consisting of 325 acids? The primary structure of the protein would be changed, the tertiary structure of the protein might be changed, and the biological activity or function of the protein might be altered.

Which of the following parts of an amino acid vary?

Which of the following parts of an amino acid vary among different amino acids? While all amino acids contain an amino group, a carboxyl group and a hydrogen bound to the central carbon, the R groups vary among the 20 different amino acids. Peptide bonds link together the amino acids of a protein’s primary structure.

What maintains the secondary structure of a protein?

Secondary structure refers to regular, recurring arrangements in space of adjacent amino acid residues in a polypeptide chain. It is maintained by hydrogen bonds between amide hydrogens and carbonyl oxygens of the peptide backbone.

What does the secondary structure of a protein do?

Secondary structure of the proteins can be used to predict the tertiary structure since predicting only with amino acid sequence may not be sufficient. The secondary structure of proteins is determined by the pattern of hydrogen bonding.

What is the function of the tertiary structure of a protein?

The tertiary structure is the structure at which polypeptide chains become functional. At this level, every protein has a specific three-dimensional shape and presents functional groups on its outer surface, allowing it to interact with other molecules, and giving it its unique function.

Which of the following is an example of tertiary structure in a protein?

Protein tertiary structure. For example, amide hydrogen atoms can form H‐bonds with nearby carbonyl oxygens; an alpha helix or beta sheet can zip up, prompted by these small local structures. Hydrophobic interactions among the amino acid side chains also determine tertiary structure.

What does the quaternary structure of a protein do?

The quaternary structure of a protein is the association of several protein chains or subunits into a closely packed arrangement. Each of the subunits has its own primary, secondary, and tertiary structure. The subunits are held together by hydrogen bonds and van der Waals forces between nonpolar side chains.

What is true of protein structure?

The primary structure of a protein involves the amino acid sequence in the polypeptide chain. The amino acids in this chain are held together by peptide bonds. The secondary structure of a protein involves the pattern of hydrogen bonds along the its peptide bond backbone, such as alpha helices and beta pleated sheets.

Which disease is a result of misfolded proteins?

Protein misfolding is believed to be the primary cause of Alzheimer’s disease, Parkinson’s disease, Huntington’s disease, Creutzfeldt-Jakob disease, cystic fibrosis, Gaucher’s disease and many other degenerative and neurodegenerative disorders.

What are the steps of protein folding?

There are four stages of protein folding, primary, secondary, tertiary and quarternary.

What is the primary structure of a protein made of?

The linear sequence of amino acids within a protein is considered the primary structure of the protein. Proteins are built from a set of only twenty amino acids, each of which has a unique side chain. The side chains of amino acids have different chemistries.